Serratia marcescens chitobiase is a retaining glycosidase utilizing substrate acetamido group participation

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Serratia marcescens chitobiase is a retaining glycosidase utilizing substrate acetamido group participation.

The stereochemistry of the reaction catalysed by Serratia marcescens chitobiase was determined by HPLC separation of the anomers of N-acetylglucosamine produced during the hydrolysis of p-nitrophenyl N-acetyl-beta-d-glucosaminide (PNP-GlcNAc). In the early stages of the reaction, the beta-anomer was found to prevail, whereas the alpha-anomer dominated at mutarotation equilibrium. This establish...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1997

ISSN: 0264-6021,1470-8728

DOI: 10.1042/bj3280945